Arylation of diazoesters by a transient N-H insertion organocascade.
نویسندگان
چکیده
It takes two: A unique organocatalyzed cascade for the unsymmetric double arylation of α-nitrodiazoesters is described. This organocascade features the strategic use of carbene-activating anilines in conjunction with a urea catalyst, thus allowing for the synthesis of pharmaceutically attractive α-diarylesters through a transient NH insertion process.
منابع مشابه
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ورودعنوان ژورنال:
- Angewandte Chemie
دوره 52 43 شماره
صفحات -
تاریخ انتشار 2013